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In the SURPASS-4 trial, adults with T2DM at heightened cardiovascular risk, who were inadequately managed with oral glucose-lowering agents, once-weekly tirzepatide (5 mg, 10 mg, or 15 mg) were compared to insulin glargine (100 U/mL)

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If you're on oral HRT and are starting, changing to, or increasing the dose of weight loss injections like Mounjaro, it's important to speak with your GP or HRT provider beforehand

They followed a strict low-FODMAP diet for 12 weeks, guided by a registered dietitian, with monthly follow-ups to assess compliance and safety